EHA Unplugged

European Hematology Association

In these EHA-produced podcasts, experts share with you their hematology knowledge and stories. With "EHA Unplugged" we would like to give you the opportunity to unplug from your computer screen, while still learning, by listening to interviews, clinical cases, monologues, and more. read less
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Episodes

Precision Medicine in Multiple Myeloma
12-04-2024
Precision Medicine in Multiple Myeloma
Join us for a captivating discussion with Prof Pieter Sonneveld, MD, PhD, from Erasmus MC Cancer Institute in Rotterdam, the Netherlands, as he explores the evolution of precision medicine in multiple myeloma. Prof. Sonneveld outlines the improvements in multiple myeloma treatment over the past decade, describing the progressive addition of targeted therapies such as daratumumab and bispecific antibodies, BiTEs, and CAR-T cells to the therapeutic arsenal. Discover how treatment selection now hinges on whether a one-off or continuous therapy is most suitable, acknowledging the challenges of limited availability in Europe due to cost considerations. Learn about the outstanding findings from the phase III PERSEUS trial, demonstrating the effectiveness of daratumumab combined with lenalidomide for newly diagnosed transplant-eligible patients and transforming their standard of care. This interview unveils cutting-edge strategies that are reshaping myeloma prognosis and underscores the importance of early adoption of novel therapies for improved patient outcomes.Host: Isabel Olivera-Martinez, PhDGuest: Prof Peter SonneveldThis is the fifth episode in a series of podcasts covering precision medicine across various disorders; more podcasts will be available in the future. Stay tuned!Learn MoreIf you'd like to learn more about Multiple Myeloma, check out the comprehensive EHA - Multiple Myeloma Program  on EHA Campus.Interested in more content related to Precision Medicine? We've got you covered. Check out podcasts, clinical cases, courses, and more on EHA Campus.What did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Precision Medicine in Myeloproliferative Neoplasms
05-04-2024
Precision Medicine in Myeloproliferative Neoplasms
Welcome to this podcast episode featuring Prof Claire Harrison (Clinical Director at Guy’s and St Thomas’ NHS Foundation Trust) and Prof Jean-Jacques Kiladjian (Professor at Université Paris-Diderot and Hôpital Saint-Louis).  Join them as they navigate the challenges and opportunities of precision medicine in MPNs, discover how advancements in molecular techniques are reshaping disease diagnosis, patient stratification and treatment tailoring.   Gain insights into the evolving landscape of targeted therapies for MPNs, including JAK inhibitors and emerging strategies for CALR mutation targeting.  Listen as our experts highlight the heterogeneity of clinical needs based on individual patients' molecular profiles and the promise of personalised treatment approaches bringing exciting prospects for improving patient outcomes in this dynamic field. Host: Isabel Olivera-Martinez, PhDGuest: Prof Claire Harrison and Prof Jean-Jacques KiladjianThis is the fourth episode in a series of podcasts covering precision medicine across various disorders; more podcasts will be available in the future. Stay tuned!Learn MoreIf you'd like to learn more about MPN, check out the EHA - Myeloproliferative Neoplasms Program  on EHA Campus.Interested in more content related to Precision Medicine? We've got you covered. Check out podcasts, clinical cases, courses, and more on EHA Campus.What did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Precision Medicine and Clonal Hematopoiesis
29-03-2024
Precision Medicine and Clonal Hematopoiesis
Join us on this podcast episode featuring Prof Helen Papadaki (University of Crete, Greece) as she discusses the link between clonal hematopoiesis and the risk of developing MDS or AML.  Prof. Papadaki begins by explaining the difference between CHIP (clonal hematopoiesis of indeterminate potential), CCUS (clonal cytopenia of undetermined significance) and ICUS (Idiopathic cytopenia of undetermined significance). She underlines the clinical relevance of the association of clonal hematopoiesis with cytopenias, as a clear indicator of an increased risk of developing hematological malignancies.  Learn how important it is to better characterize by NGS sequencing the specific mutations of the clones, given that the type of mutation, the number of mutations, and the combination of mutations are critical parameters in accurately predicting the risk of developing MDS or AML.  Furthermore, Prof Papadaki explains the importance of discriminating between acquired and germline mutations leading to clonal hematopoiesis and their relationship with age. Finally, she highlights the fact that clonal hematopoiesis is a risk factor for developing not only hematological malignancies but also cardiac diseases. Host: Isabel Olivera-Martinez, PhDGuest: Prof Helen PapadakiThis is the third episode in a series of podcasts covering precision medicine across various disorders; more podcasts will be available in the future. Stay tuned!Learn More  What did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Precision Medicine: Hepcidin Mimetics for Polycythemia Vera Treatment
15-03-2024
Precision Medicine: Hepcidin Mimetics for Polycythemia Vera Treatment
Join us on this podcast episode featuring Prof Domenico Girelli,  Professor of Internal Medicine and Director of the Internal Medicine Unit, University Hospital of Verona (Italy), as he discusses the latest advances on the use of Hepcidin mimetics in the treatment of Polycythemia Vera and iron metabolism diseases. Discover how Hepcidin analogues offer a precise method for managing the overproduction of red blood cells in Polycythemia Vera patients. Explore the potential of Rusfertide, an inhibitor of Hepcidin, in regulating iron availability for erythropoiesis, thereby addressing the characteristic and chronic erythrocytosis seen in Polycythemia Vera. Gain insights into how targeting the Hepcidin-Ferroportin axis is revolutionizing the treatment of various iron metabolism disorders. Tune in for a comprehensive discussion on these groundbreaking advancements in hematology research. Host: Isabel Olivera-Martinez, PhDGuest: Prof Domenico GirelliThis is the second in a series of podcasts covering precision medicine across various disorders; more podcasts will be available in the future. Stay tuned!  Learn MoreTo go further: Kremyanskaya M et al. Rusfertide, a Hepcidin Mimetic, for Control of Erythrocytosis in Polycythemia Vera. N Engl J Med. 2024 Feb 22;390(8):723-735. doi: 10.1056/NEJMoa2308809. PMID: 38381675.What did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Precision Medicine in Inherited Bone Marrow Failure Syndromes
16-02-2024
Precision Medicine in Inherited Bone Marrow Failure Syndromes
Welcome to another season of EHA Unplugged. In our first episode of 2024, listen to Prof Carlo Dufour, Chairperson of the Paediatric Hemato-Oncology department of G. Gaslini Children’s Hospital in Genova (Italy), as he discusses how classical IBMFs (such as Fanconi Anemia, Diamond-Blackfan Anemia, Shwachman-Diamond Syndrome, and the telomere disorders) are now being joined by a large number of other diseases included in this category, thanks to the increasing precision of diagnostic genetic tools. Prof Dufour explains further how crucial precise genetic-based diagnosis is in discriminating between true acquired and constitutional bone marrow failure disorders in order to properly determine the best line of treatment for these rare diseases and to establish a monitoring plan to prevent the occurrence of secondary malignancies. Tune in to find out how IBMFS patients may benefit from precision medicine and a therapy tailored to their genetic constitution. This is a series of podcasts covering precision medicine across various disorders, more podcasts will be available in the future. Stay tuned!  Guest: Prof Carlo Dufour, G. Gaslini Children’s Hospital in Genova (Italy)Host: Isabel Olivera-Martinez, PhD, European Hematology Association (EHA)Learn MoreTo go further: Miano M, Grossi A, Dell'Orso G, et al. Genetic screening of children with marrow failure. The role of primary Immunodeficiencies. Am J Hematol. 2021; 96(9): 1077–1086. https://doi.org/10.1002/ajh.26242  What did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Unraveling Autoimmune Neutropenia: From Childhood to Adulthood
03-11-2023
Unraveling Autoimmune Neutropenia: From Childhood to Adulthood
Join us for this update on Autoimmune Neutropenia (AIN), a rare blood disorder that presents and develops differently in children and adults. Experts Dr Francesca Fioredda and Prof Helen Papadaki along with our host Dr. Isabel Olivera discuss the diagnostic challenges associated with AIN and the need for a broader definition, based on the latest insights from the different mechanisms underlying AIN’s pathogenesis.Learn how to adapt the treatment of AIN to the specific form of neutropenia, the patient’s age, evolving needs, and underlying disease. Our experts also emphasize the importance of carefully monitoring AIN patients and of maintaining accurate patient registries.Read this review article on AIN at HemaSphere or follow the AIN course on the EHA Campus to learn more about AIN.​​​​​​​Host:Dr. Isabel OliveraEuropean Hematology AssociationGuests:Dr Francesca Fioredda​Istituito Giannina Gaslini, ItalyProf Helen Papadaki​University of Crete School of Medicine, GreeceLearn MoreWhat did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Navigating the World of Hematology Research: from Mentorship to Work-Life Balance
27-10-2023
Navigating the World of Hematology Research: from Mentorship to Work-Life Balance
Join us in this enlightening podcast as three experienced researchers, Dr Anastasia Conti, Prof Konstanze Döhner, and Dr Simona Valletta​, delve into the dynamic world of scientific research. This discussion moderated by Prof Kirsten Grønbæk offers valuable insights into the pivotal aspects of successful careers in research for hematologists.The conversation dives deeply into topics relevant to aspiring and established researchers, such as the crucial role of mentorship, and the importance of female mentors in the field, as they may offer valuable guidance to women in science. Choosing the right research lab, the need for a work-life balance, and how to balance clinical work with research endeavors for clinician-scientists are other valuable insights shared by the panel.The podcast concludes with a focus on fostering a supportive work environment for researchers. They emphasize flexibility, strong communication, and the importance of respecting boundaries to maintain a positive and productive lab atmosphere.Tune in to gain a wealth of knowledge for navigating in the world of scientific research in hematology.Host: Prof Kirsten Grønbæk ​Rigshospitalet and BRIC, Denmark​Guests: Dr Anastasia Conti ​San Raffaele Telethon Institute for Gene Therapy, Italy​​Prof Konstanze Döhner ​University Hospital of Ulm, Ulm, Germany ​​Dr Simona Valletta​University of Manchester, United KingdomLearn MoreWhat did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
Patient Communication and Self Care
09-10-2023
Patient Communication and Self Care
Join us for this insightful podcast where our experts Prof Kirsten Grønbæk, Dr Mirjam Belderbos, Dr Umut Yilmaz, and Prof Konstanze Döhner discuss their experiences, challenges, and strategies for thriving in their demanding and rewarding careers as hematologists. They share valuable insight from effective communication with patients and caregivers to coping with the emotional aspects of their work. Discover how they strike a balance between personal well-being and professional responsibilities.Host:Prof Kirsten Grønbæk, Rigshospitalet and BRIC, Copenhagen, DenmarkGuests:Dr Umut Yilmazİstanbul University-Cerrahpaşa, Istanbul, Turkey Prof Konstanze Döhner University Hospital of Ulm, Ulm, Germany Dr Mirjam Belderbos Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands Learn MoreIf you'd like to continue learning about patient communication, check out the course The Divided Brain: Emotion vs. Logic in Patient Communication on EHA Campus.What did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe
How to Get Started in Hematology Research - Dr Anastasia Conti, Assoc Prof Maria Paola Martelli and Dr Simona Valletta
08-09-2023
How to Get Started in Hematology Research - Dr Anastasia Conti, Assoc Prof Maria Paola Martelli and Dr Simona Valletta
Our guests Dr Anastasia Conti, Assoc Prof Maria Paola Martelli and Dr Simona Valletta give an overview on starting research in hematology. They go through their experience, give advice and talk about the challenges they face. The podcast starts with the basics of how to get started in hematology research, starting how to come up with research ideas and how to develop these ideas into projects. Our guests continue with their view on PhD programmes, where they give advice to those who want to start a PhD or a research focused career. Anastasia, Maria and Simona recollects how rewarding their PhD experience was and emphasizes the importance of motivation, resilience and persistence in research. A PhD shapes you Simona says. Last but not least, they delve into the topic of research funding and their experiences in writing grants. Guests: Dr Anatasia Conti San Raffaele Telethon Institute for Gene Therapy, Milan, ItalyAssoc Prof Maria Paola MartelliUniversity of Perugia, Perugia, ItalyDr Simona VallettaUniversity of Manchester, Manchester, United KingdomHost: Prof Kirsten GrønbækRigshospitalet and BRIC, Copenhagen, DenmarkWhat did you think of this podcast? Share your opinions with us in this short feedback survey.Provide FeedbackWould you like to explore more eLearning or podcasts? Please visit the EHA Campus.https://ehaedu.org/CampusSubscribe, share, and review this podcast to be able to address topics you enjoy and like to listen to.Follow EHA on Instagram: https://www.instagram.com/EHA_Hematology/Facebook: https://e-h-a.link/facebookLinkedIn: https://www.linkedin.com/company/eha/Email us: education@ehaweb.orgSubscribe to receive the EHA Educational Updates via https://eha.news/subscribe