With the emergence of new variants of the coronavirus, including Delta, COVID-19​​ continues to spread rapidly across much of the world. In most U.S. states, a surge in cases is reigniting conversations about the country’s response to the pandemic. Dr. Alok Patel speaks with a leading epidemiologist and a specialist in infectious diseases to gain perspective on pressing concerns, from vaccine effectiveness and boosters to vaccine hesitancy, misinformation, and inequity at a national and global scale.